Understanding the factors associated with reduction in the number of lymph nodes in rectal cancer patients treated by neoadjuvant treatment
Int J Colorectal Dis. 2017 Jun;32(6):925-927. doi: 10.1007/s00384-016-2747-7. Epub 2016 Dec 29. Understanding the factors associated with reduction in the number of lymph nodes in rectal cancer patients treated by neoadjuvant treatment. Bustamante-Lopez L 1 , Nahas CS 2 , Nahas SC 2 , Ribeiro U Jr 2 , Marques CF 2 , Cotti G 2 , Rocco A 2 , Cecconello I 2 . Author information Abstract INTRODUCTION: Rectal cancer patients frequently present with locally advanced disease for which the standard of care includes neoadjuvant chemoradiotherapy followed by total mesorectal excision. Positive lymph nodes are one of the most powerful risk factors for recurrence and survival in colorectal cancer. In the absence of specific rectal guidelines, the literature recommends to the pathologist to optimize the number of rectal lymph nodes (LN) retrieved. We made a literature review in order to identify factors that could potentially affect...